In most cases, OA is a slowly progressive condition and cannot be cured, but it can be well managed allowing continued athletic function in many horses. Anti-inflammatory drugs are the mainstay of most treatments for OA. They act by reducing inflammation and provide pain relief. Most of their action is in blocking some of the inflammatory mediators produced in affected joints.
Interleukin-1 receptor antagonist protein (IRAP) is a collection of proteins derived from a blood sample taken from the horse being treated.
Glucocorticoids have ant-inflammatory activity by inhibiting inflammatory mediator and destructive enzyme production.
IRAP is one of the new biological treatments utilising the patient’s own biochemical proteins to suppress the inflammatory reaction in osteoarthritic joints.
Bisposhonates are medications which suppresses the action of the bone reabsorbing cells (Osteoclasts) and subdues the mediators in joint inflammation and destruction.
If you are concerned that your horse may be experiencing any of the issues described on this page, we would encourage you to talk through these concerns with your vet.